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The World Health Organization classifies India as intermediate prevalence zone with prevalence rates ranging between 2% and 7%.
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However, combination therapy cannot be recommended for pediatric HBV infection until more data are available ( DII).
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However, these data suggest that some ART drugs may not achieve sufficient concentrations in mucosal tissues to completely suppress local replication of HIV and, accordingly, may not be sufficient to prevent acquisition of HIV.
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Successful discontinuation of the placebo arm and provision of an effective HIV prevention product after a positive interim efficacy result.
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This class of drugs includes saquinavir (Invirase), nelfinavir (Viracept), ritonavir (Norvir), tipranavir (Aptivus), indinavir (Crixivan), amprenavir (Agenerase), and atazanavir (Reyataz).
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Last, reversal agents (naloxone and flumazenil) and respiratory support should always be available for use if necessary.
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The efficacy and safety of switching from a ritonavir-boosted protease inhibitor in combination with two NRTIs to Complera was evaluated in Study 106, a randomized, open-label study in virologically-suppressed HIV-1-infected adults.
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Additionally, the vast majority of infected cells are not undergoing lytic replication, and antiherpes medications have had little or no effect on established KS or HHV-8 cellular viremia.
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Continuation of PrEP during pregnancy is an individualized decision based on patient preference and whether there are ongoing risks for HIV during pregnancy.
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Drug susceptibility results quantify the impact of a mutation or combination of mutations in vitro.
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Elbasvir and grazoprevir demonstrated superior efficacy especially in subgroups of patients considered as hard-to-treat in the past (in cirrhotics, patients with high initial vireamia and in previous null-responders to pegylated interferon and ribavirin).
Treatment should resume if these parameters are not met.
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BOSTON -- A drug combination cured only a small fraction of patients with chronic hepatitis B (HBV), a researcher said here.
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