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As with other drugs in this class, some isolates of Pseudomonas aeruginosa may develop resistance fairly rapidly during treatment with Levofloxacin.

The median time to resolution was 7 days for Levofloxacin-treated children and 9 for non-fluoroquinolone-treated children (approximately 80% resolved within 2 months in both groups).

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Medical Gastroenterology CA-2121, RIGSHOSPITALET, Copenhagen, Denmark, 2University of Pennsylvania, Philadelphia, PA, 3Emory University School of Medicine, Atlanta, GA, United States, 4Charité University Medical Center, Berlin, Germany, 5Mount Sinai Medical Center, New York, NY, United States, 6M.

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The microbiologically evaluable (ME) population included CE patients for whom at least one isolate was identified from the baseline culture that was susceptible to both test drugs and who had a microbiologic response that could be classified as eradication, persistence, or superinfection at the test-of-cure visit.

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