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How long does it take for Nexium to work on an ulcer? PPIs (proton pump inhibitors), like Nexium 24HR, treat frequent heartburn by blocking the production of stomach acid. PPIs may take 1-4 days for full effect, but relief lasts for 24 hours. Nexium 24HR may take 1-4 days for full effect, which is 24 hours of complete relief ^ from frequent heartburn.
Can pantoprazole be taken with food? Pantoprazole tablets are taken by mouth, with or without food. Pantoprazole oral granules should be taken 30 minutes before a meal. Do not crush, chew, or break the tablet. Swallow it whole.
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