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It is better to discuss whatever questions you have with your doctor and follow his recommendations.
Do not use more than directed.
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For all other analyses (including MACE and COPD exacerbations), only events with onset in the on-treatment period were noted (on-treatment analysis).
The primary mortality analysis (modified intention-to-treat analysis) involved all patients who received at least one dose of a study drug, regardless of whether the patient discontinued the drug prematurely.
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This should lead to utilization of the least possible dose of medications in order to minimize the risk of side effects.
Van de Maele B, Fabbri LM, Martin C, Horton R, Dolker M, Overend T: Cardiovascular safety of QVA149, a combination of indacaterol and NVA237, in COPD patients.
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Lung volume reduction surgery and improvement of endothelial function and blood pressure in patients with chronic obstructive pulmonary disease: a randomized controlled trial.
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Adding LTRA to the combination of high-dose ICS and LABA is recommended for consideration (Evidence B).
Patients with more severe cases should use them in combination with other drugs.
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The original manufacturer uses a brand name whereas a generic drug is usually called by the name of the active ingredient.
An anticholinergic agent is a type of drug that blocks the action of acetylcholine in certain parts of body.
Every care has been taken to provide accurate details on this web site, however minor discrepancies may appear.
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Geller DE: Comparing clinical features of the nebulizer, metered-dose inhaler, and dry powder inhaler.
An increased need for medication could be an early sign that your condition is getting worse.
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Salmeterol-fluticasone (Advair), formoterol-budesonide (Symbicort), and formoterol-mometasone (Dulera) are long-acting beta2 agonists products combined with a steroid in a single inhaler that are used for treatment of moderate-to-severe asthma.
However, because of the disadvantages outlined above, administration of theophylline should be continued only if its efficacy on the symptoms has been demonstrated.
Efficacy of Uniphyl, salbutamol, and their combination in asthmatic patients on high-dose inhaled steroids.
One 10-day course of oral steroids was permitted for the treatment of a COPD exacerbation during the study period.
Whether the observed differences might be due to differences in the aerosolizing systems, the particle size of the aerosols, or the distribution of the drug in the lung is also unknown.
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The summary below is from the full reports titled “Diagnosis and Management of Stable Chronic Obstructive Pulmonary Disease: A Clinical Practice Guideline from the American College of Physicians” and “Management of Stable Chronic Obstructive Pulmonary Disease: A Systematic Review for a Clinical Practice Guideline.
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Meier Estimates of the Probability of COPD Exacerbation and Death from Any Cause.
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Patients should not use it for self-medication without the advice of a doctor.
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Casaburi R, Briggs DD, Donohue JF, Serby CW, Menjoge SS, Witek TJ, for the US Tiotropium Study Group: The spirometric efficacy of once-daily dosing with tiotropium in stable COPD.
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However, in rats the drug caused such effects as fetal resorption, litter loss and decreases in the number of live pups at birth.
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Improvements in COPD symptoms were consistently numerically greater with aclidinium versus tiotropium.
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A generic drug is usually called by the name of the active ingredient while a manufacturer uses a brand name.
Books About COPD -- for a General Audience (With links to Amazon.
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FEV 1, as the same total daily dose administered twice daily.
Once you notice a side effect (or one is found by your doctor using laboratory tests), the severity of your side effects must be weighed against the benefit obtained by continuing the drug.
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Safety of inhaled corticosteroids for treating chronic obstructive pulmonary disease.
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Long-acting bronchodilators help to control and prevent symptoms.
Ethnic differences in the effect of asthma on pulmonary function in children.
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The advise treating most COPD exacerbations with 40 mg prednisone for 5 days.
Comparison of other baseline characteristics from the TIOSPIR anticholinergic-naive subpopulation with those from the UNLOCK cohort and combined RCTs indicate that this subgroup may have greater similarity to the UNLOCK population than other large COPD trials.
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The Nationwide Drug Code (NDC) is a quantity utilized by the pharmacist to determine the drug and the method of packaging. This info always appears on the label at either the highest left, the top proper, or on the backside.
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