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Chloroquine (Aralen) may be used safely in all trimesters of pregnancy, and mefloquine may be used safely in the second and third trimesters of pregnancy.
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N-dimethylglycylamido)-6-demethyl-6-deoxytetracycline was unable to reach the normal inducer binding position within the repressor, as a result of a weakened hydrogen-bonding pattern within and around the tetracycline binding site.
Dave has promised to find local health remedies as he travels and report back to Earth Clinic any interesting suggestions!
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Mefloquine specifically targets lysosomal function and accumulates in lysosomes of the malarial parasite.
This is why DDT is still allowed to be used for controlling malaria.
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Not only is chloroquine an effective drug--probably due to its site of action in the food vacuole and its interference with hemozoin formation (see )--but it is also relatively non-toxic and cheap.
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Indians, have used this bark and have healed many of those with it.
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Nevin studies conclude that mefloquine can cause obvious brain injuries in some veterans, like Jimmy Corrigan, but less obvious changes to mood and personality in thousands of veterans, like Sean Laraway.
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As an alternative, the related compound hydroxychloroquine sulfate may be better tolerated.
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The editor has therefore updated the information in the questions to reflect that in the current BNF, so as to ensure that the questions are practical and contemporary.
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